The X3-2M is a PCI Express XMC IO module featuring 12 simultaneously sampling 16-bit, 10 MSPS A/D channels and an FPGA processing core. It is designed for high speed instrumentation and analysis for neuro-physical, RADAR, and high speed data acquisition applications.Flexible trigger methods include counted frames, software triggering and external triggering. The sample rate clock is either an external clock or on-board programmable PLL clock source.Data acquisition control, signal processing, buffering, and system interface functions are implemented in a Xilinx Spartan3A DSP FPGA, 1.8M gate device. Two 512Kx32 memory devices are used for data buffering and FPGA computing memory.The logic can be fully customized using VHDL and MATLAB using the FrameWork Logic toolset. The MATLAB BSP supports real-time hardware-in-the-loop development using the graphical, block diagram Simulink environment with Xilinx System Generator.The PCI Express interface supports continuous data rates up to 220 MB/ s between the module and the host. A flexible data packet system implemented over the PCIe interface provides both high data rates to the host that is readily expandable for custom applications.